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LYTAK1, a TAK1 inhibitor, suppresses proliferation and epithelial-mesenchymal transition in retinal pigment epithelium cells

The proliferation of retinal pigment epithelium (RPE) cells following epithelial-mesenchymal transition (EMT) is critical in proliferative vitreoretinopathy (PVR), which results in retinal detachment and the loss of vision. The current study was conducted to examine the importance of transforming gr...

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Detalles Bibliográficos
Autores principales: CHEN, ZHEN, MEI, YAN, LEI, HUO, TIAN, RUN, NI, NINGHUA, HAN, FANG, GAN, SHENGWEI, SUN, SHANQUAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918529/
https://www.ncbi.nlm.nih.gov/pubmed/27175834
http://dx.doi.org/10.3892/mmr.2016.5275