Cargando…

LYTAK1, a TAK1 inhibitor, suppresses proliferation and epithelial-mesenchymal transition in retinal pigment epithelium cells

The proliferation of retinal pigment epithelium (RPE) cells following epithelial-mesenchymal transition (EMT) is critical in proliferative vitreoretinopathy (PVR), which results in retinal detachment and the loss of vision. The current study was conducted to examine the importance of transforming gr...

Descripción completa

Detalles Bibliográficos
Autores principales:	CHEN, ZHEN, MEI, YAN, LEI, HUO, TIAN, RUN, NI, NINGHUA, HAN, FANG, GAN, SHENGWEI, SUN, SHANQUAN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918529/ https://www.ncbi.nlm.nih.gov/pubmed/27175834 http://dx.doi.org/10.3892/mmr.2016.5275

Ejemplares similares

LYTAK1 attenuates proliferation of retinal pigment epithelial cells through TGF-β-mediated epithelial-mesenchymal transition via the ERK/AKT signaling pathway
por: Chen, Zhen, et al.
Publicado: (2017)

Role of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelium Dysfunction
por: Zhou, Mi, et al.
Publicado: (2020)

A FOXM1 Dependent Mesenchymal-Epithelial Transition in Retinal Pigment Epithelium Cells
por: Choudhary, Parul, et al.
Publicado: (2015)

DAPL1 prevents epithelial–mesenchymal transition in the retinal pigment epithelium and experimental proliferative vitreoretinopathy
por: Ma, Xiaoyin, et al.
Publicado: (2023)

Resveratrol inhibits epithelial-mesenchymal transition of retinal pigment epithelium and development of proliferative vitreoretinopathy
por: Ishikawa, Keijiro, et al.
Publicado: (2015)

Autophagy regulates TGF-β2-induced epithelial-mesenchymal transition in human retinal pigment epithelium cells
por: Wu, Jing, et al.
Publicado: (2018)

Proteome Landscape of Epithelial-to-Mesenchymal Transition (EMT) of Retinal Pigment Epithelium Shares Commonalities With Malignancy-Associated EMT
por: Sripathi, Srinivasa R., et al.
Publicado: (2021)

IKKβ Inhibition Attenuates Epithelial Mesenchymal Transition of Human Stem Cell-Derived Retinal Pigment Epithelium
por: Sripathi, Srinivasa R., et al.
Publicado: (2023)

Trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial–mesenchymal transition in retinal pigment epithelium cells
por: Xiao, Wei, et al.
Publicado: (2014)

Transcriptional regulatory network analysis during epithelial-mesenchymal transformation of retinal pigment epithelium
por: Pratt, Craig H., et al.
Publicado: (2008)

Epithelial-Mesenchymal Transition and Senescence in the Retinal Pigment Epithelium of NFE2L2/PGC-1α Double Knock-Out Mice
por: Blasiak, Janusz, et al.
Publicado: (2021)

Polarity and epithelial-mesenchymal transition of retinal pigment epithelial cells in proliferative vitreoretinopathy
por: Zou, Hui, et al.
Publicado: (2020)

Role of Epithelial-to-Mesenchymal Transition of Retinal Pigment Epithelial Cells in Glaucoma Cupping
por: O’Driscoll, Eabha, et al.
Publicado: (2023)

Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration
por: Tian, Haibin, et al.
Publicado: (2022)

Role of LINC01592 in TGF-β1-induced epithelial-mesenchymal transition of retinal pigment epithelial cells
por: Su, Ying, et al.
Publicado: (2021)

Suppression of choroidal neovascularization and epithelial-mesenchymal transition in retinal pigmented epithelium by adeno-associated virus-mediated overexpression of CCN5 in mice
por: Im, Sora, et al.
Publicado: (2022)

Expression of pigment epithelium‐derived factor and thrombospondin‐1 regulate proliferation and migration of retinal pigment epithelial cells
por: Farnoodian, Mitra, et al.
Publicado: (2015)

Snail Involves in the Transforming Growth Factor β1-Mediated Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells
por: Li, Hui, et al.
Publicado: (2011)

Evaluation of focal damage in the retinal pigment epithelium layer in serous retinal pigment epithelium detachment
por: Miura, Masahiro, et al.
Publicado: (2019)

Taurine rescues mitochondria-related metabolic impairments in the patient-derived induced pluripotent stem cells and epithelial-mesenchymal transition in the retinal pigment epithelium
por: Homma, Kohei, et al.
Publicado: (2021)

Correction: Suppression of choroidal neovascularization and epithelial-mesenchymal transition in retinal pigmented epithelium by adeno-associated virus-mediated overexpression of CCN5 in mice
por: Im, Sora, et al.
Publicado: (2023)

The Complex Interplay between ERK1/2, TGFβ/Smad, and Jagged/Notch Signaling Pathways in the Regulation of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelium Cells
por: Chen, Xiaoyun, et al.
Publicado: (2014)

The Retinal Pigment Epithelium: a Convenient Source of New Photoreceptor cells?
por: Wang, Shu-Zhen, et al.
Publicado: (2014)

Inhibitory Effects of Plumbagin on Retinal Pigment Epithelial Cell Epithelial-Mesenchymal Transition In Vitro and In Vivo
por: Chen, Haitin, et al.
Publicado: (2018)

Deficiency of pigment epithelium-derived factor in nasopharyngeal carcinoma cells triggers the epithelial–mesenchymal transition and metastasis
por: Zhang, Ting, et al.
Publicado: (2017)

Translocation of the retinal pigment epithelium and formation of sub-retinal pigment epithelium deposit induced by subretinal deposit
por: Zhao, Lian, et al.
Publicado: (2007)

NURR1 expression regulates retinal pigment epithelial–mesenchymal transition and age-related macular degeneration phenotypes
por: Yao, Pei-Li, et al.
Publicado: (2022)

Inhibitory Effect of Bone Morphogenetic Protein 4 in Retinal Pigment Epithelial-Mesenchymal Transition
por: Yao, Haipei, et al.
Publicado: (2016)

Suppressive effect of AMP-activated protein kinase on the epithelial-mesenchymal transition in retinal pigment epithelial cells
por: Matoba, Ryo, et al.
Publicado: (2017)

Exosomes mediate an epithelial‐mesenchymal transition cascade in retinal pigment epithelial cells: Implications for proliferative vitreoretinopathy
por: Zhang, Yao, et al.
Publicado: (2020)

Function of the Retinal Pigment Epithelium in Patients With Neurofibromatosis Type 1
por: Touzé, Romain, et al.
Publicado: (2022)

Oxidation of DJ-1 Cysteines in Retinal Pigment Epithelium Function
por: Bhattacharyya, Sanghamitra, et al.
Publicado: (2022)

Setting Eyes on the Retinal Pigment Epithelium
por: Moreno-Marmol, Tania, et al.
Publicado: (2018)

Functions and Diseases of the Retinal Pigment Epithelium
por: Yang, Song, et al.
Publicado: (2021)

Correction: Deficiency of pigment epithelium-derived factor in nasopharyngeal carcinoma cells triggers the epithelial–mesenchymal transition and metastasis
por: Zhang, Ting, et al.
Publicado: (2018)

Evaluation of retinal pigment epithelium changes in serous pigment epithelial detachment in age-related macular degeneration
por: Miura, Masahiro, et al.
Publicado: (2021)

Bestrophin 2 is expressed in human non-pigmented ciliary epithelium but not retinal pigment epithelium
por: Zhang, Youwen, et al.
Publicado: (2010)

Detection of Retinal Pigment Epithelium-Specific Antibody in iPSC-Derived Retinal Pigment Epithelium Transplantation Models
por: Sugita, Sunao, et al.
Publicado: (2017)

Impact of drusen and drusenoid retinal pigment epithelium elevation size and structure on the integrity of the retinal pigment epithelium layer
por: Schlanitz, Ferdinand, et al.
Publicado: (2019)

Common clinical features of unilateral retinal pigment epithelium dysgenesis and combined hamartoma of the retina and retinal pigment epithelium
por: Zhu, Zhe, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_tbml2vvdgmoo07fgb9t0cia0cl