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Nonsense-mediated mRNA decay factor Upf2 exists in both the nucleoplasm and the cytoplasm

Upf2 protein predominantly localizes to the cytoplasmic fraction, and binds to the exon junction complex (EJC) on spliced mRNA. The present study aimed to determine the cellular site where the interaction between Upf2 and EJC occurs. First, the cell lysate was fractionated into the cytoplasm and nuc...

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Detalles Bibliográficos
Autores principales: TATSUNO, TAKANORI, NAKAMURA, YUKA, MA, SHAOFU, TOMOSUGI, NAOHISA, ISHIGAKI, YASUHITO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918542/
https://www.ncbi.nlm.nih.gov/pubmed/27221324
http://dx.doi.org/10.3892/mmr.2016.5331