Cargando…

Iptakalim influences the proliferation and apoptosis of human pulmonary artery smooth muscle cells

The aim of the present study was to determine the effect of an ATP-sensitive K(+) (K(ATP)) channel opener iptakalim (IPT) on the proliferation and apoptosis of human pulmonary artery smooth muscle cells (HPASMCs), and examine the potential value of IPT to hypoxic pulmonary hypertension (HPH) at a ce...

Descripción completa

Detalles Bibliográficos
Autores principales:	LI, QINGLIN, YAN, XIAOPEI, KONG, HUI, XIE, WEIPING, WANG, HONG
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918544/ https://www.ncbi.nlm.nih.gov/pubmed/27221642 http://dx.doi.org/10.3892/mmr.2016.5333

Ejemplares similares

Iptakalim, a novel ATP-sensitive potassium channel opener, inhibits pulmonary arterial smooth muscle cell proliferation by downregulation of PKC-α()
por: Zuo, Xiangrong, et al.
Publicado: (2011)

Iptakalim: A novel multi-utility potassium channel opener
por: Sikka, Pranav, et al.
Publicado: (2012)

Krüppel-like Factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension
por: Courboulin, Audrey, et al.
Publicado: (2011)

Fasudil Dichloroacetate Alleviates SU5416/Hypoxia-Induced Pulmonary Arterial Hypertension by Ameliorating Dysfunction of Pulmonary Arterial Smooth Muscle Cells
por: Liu, Ping, et al.
Publicado: (2021)

Dexamethasone induces apoptosis in pulmonary arterial smooth muscle cells
por: Price, Laura C., et al.
Publicado: (2015)

Adrenomedullin and adrenotensin regulate collagen synthesis and proliferation in pulmonary arterial smooth muscle cells
por: Li, W., et al.
Publicado: (2013)

Inhibition of KIR2.1 decreases pulmonary artery smooth muscle cell proliferation and migration
por: Cao, Nan, et al.
Publicado: (2022)

Zinc-mediated activation of CREB pathway in proliferation of pulmonary artery smooth muscle cells in pulmonary hypertension
por: Xiao, Genfa, et al.
Publicado: (2021)

Effect of miR-29b on the Proliferation and Apoptosis of Pulmonary Artery Smooth Muscle Cells by Targeting Mcl-1 and CCND2
por: Chen, Juan, et al.
Publicado: (2018)

Mir-206 Regulates Pulmonary Artery Smooth Muscle Cell Proliferation and Differentiation
por: Jalali, Samuel, et al.
Publicado: (2012)

The Hepcidin/Ferroportin axis modulates proliferation of pulmonary artery smooth muscle cells
por: Ramakrishnan, Latha, et al.
Publicado: (2018)

Upregulation of IRF9 Contributes to Pulmonary Artery Smooth Muscle Cell Proliferation During Pulmonary Arterial Hypertension
por: Chen, Yong-Jie, et al.
Publicado: (2021)

Puerarin Induces Mitochondria-Dependent Apoptosis in Hypoxic Human Pulmonary Arterial Smooth Muscle Cells
por: Chen, Chan, et al.
Publicado: (2012)

Enhancer of Zeste Homolog 2 Induces Pulmonary Artery Smooth Muscle Cell Proliferation
por: Aljubran, Salman A., et al.
Publicado: (2012)

Egr-1 mediates leptin-induced PPARγ reduction and proliferation of pulmonary artery smooth muscle cells
por: Xie, Xinming, et al.
Publicado: (2018)

Participation of PLK1 and FOXM1 in the hyperplastic proliferation of pulmonary artery smooth muscle cells in pulmonary arterial hypertension
por: Wilson, Jamie L., et al.
Publicado: (2019)

Upregulated miR-17 Regulates Hypoxia-Mediated Human Pulmonary Artery Smooth Muscle Cell Proliferation and Apoptosis by Targeting Mitofusin 2
por: Lu, Zheng, et al.
Publicado: (2016)

miR-760 mediates hypoxia-induced proliferation and apoptosis of human pulmonary artery smooth muscle cells via targeting TLR4
por: Yang, Yu-Zhong, et al.
Publicado: (2018)

Expression of mutant BMPR-II in pulmonary endothelial cells promotes apoptosis and a release of factors that stimulate proliferation of pulmonary arterial smooth muscle cells
por: Yang, Xudong, et al.
Publicado: (2011)

Endogenous Estrogen Attenuates Hypoxia-Induced Pulmonary Hypertension by Inhibiting Pulmonary Arterial Vasoconstriction and Pulmonary Arterial Smooth Muscle Cells Proliferation
por: Xu, Dunquan, et al.
Publicado: (2013)

Cigarette smoke extract stimulates human pulmonary artery smooth muscle cell proliferation: Role of inflammation and oxidative stress
por: Wang, Juan, et al.
Publicado: (2022)

Cysteine-rich 61 (Cyr61) upregulated in pulmonary arterial hypertension promotes the proliferation of pulmonary artery smooth muscle cells
por: Gao, Lan, et al.
Publicado: (2017)

Correction: Enhancer of Zeste Homolog 2 Induces Pulmonary Artery Smooth Muscle Cell Proliferation
por: Aljubran, Salman A., et al.
Publicado: (2012)

PDGF mediates pulmonary arterial smooth muscle cell proliferation and migration by regulating NFATc2
por: Zhao, Fang-Yun, et al.
Publicado: (2021)

Traditional Chinese medicine monomers: Targeting pulmonary artery smooth muscle cells proliferation to treat pulmonary hypertension
por: Yang, Xiuli, et al.
Publicado: (2023)

The inhibitory effect of Isoliquiritigenin on the proliferation of human arterial smooth muscle cell
por: Chen, Tianbao, et al.
Publicado: (2017)

Pulmonary Artery Smooth Muscle Cell Senescence Promotes the Proliferation of PASMCs by Paracrine IL-6 in Hypoxia-Induced Pulmonary Hypertension
por: Wang, Ai-Ping, et al.
Publicado: (2021)

Iptakalim Preferentially Decreases Nicotine-induced Hyperlocomotion in Phencyclidine-sensitized Rats: A Potential Dual Action against Nicotine Addiction and Psychosis
por: Volf, Nick, et al.
Publicado: (2012)

Akt-Dependent Glycolysis-Driven Lipogenesis Supports Proliferation and Survival of Human Pulmonary Arterial Smooth Muscle Cells in Pulmonary Hypertension
por: Jiang, Lifeng, et al.
Publicado: (2022)

Differential effects of formoterol on thrombin- and PDGF-induced proliferation of human pulmonary arterial vascular smooth muscle cells
por: Goncharova, Elena A, et al.
Publicado: (2012)

S1P induces proliferation of pulmonary artery smooth muscle cells by promoting YAP-induced Notch3 expression and activation
por: Wang, Jian, et al.
Publicado: (2021)

Glycogen Synthase Kinase 3beta Contributes to Proliferation of Arterial Smooth Muscle Cells in Pulmonary Hypertension
por: Sklepkiewicz, Piotr, et al.
Publicado: (2011)

Inhibitory effect of Bailing capsule on hypoxia-induced proliferation of rat pulmonary arterial smooth muscle cells
por: Li, Xiaohui, et al.
Publicado: (2016)

MiR‐339 inhibits proliferation of pulmonary artery smooth muscle cell by targeting FGF signaling
por: Chen, Jidong, et al.
Publicado: (2017)

Chemerin Added to Endothelin-1 Promotes Rat Pulmonary Artery Smooth Muscle Cell Proliferation and Migration
por: Hanthazi, Aliénor, et al.
Publicado: (2020)

JMJD1C promotes smooth muscle cell proliferation by activating glycolysis in pulmonary arterial hypertension
por: Zhang, Chen, et al.
Publicado: (2023)

Chemerin Regulates the Proliferation and Migration of Pulmonary Arterial Smooth Muscle Cells via the ERK1/2 Signaling Pathway
por: Peng, Linqian, et al.
Publicado: (2022)

Influence of Carbon Monoxide on Growth and Apoptosis of Human Umbilical Artery Smooth Muscle Cells and Vein Endothelial Cells
por: Li, Yajuan, et al.
Publicado: (2012)

The Role and Regulation of Pulmonary Artery Smooth Muscle Cells in Pulmonary Hypertension
por: He, Shixin, et al.
Publicado: (2020)

Cytokine regulation of apoptosis-induced apoptosis and apoptosis-induced cell proliferation in vascular smooth muscle cells
por: Aravani, Dimitra, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_e29d33kafs7no64g5fmn35epd7