BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers

T cell antigen receptor (TCR) signaling drives distinct responses depending upon the differentiation state and context of CD8(+) T cells. We hypothesized that access of signal-dependent transcription factors (TFs) to enhancers is dynamically regulated to shape transcriptional responses to TCR signal...

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Detalles Bibliográficos
Autores principales: Roychoudhuri, Rahul, Clever, David, Li, Peng, Wakabayashi, Yoshiyuki, Quinn, Kylie M., Klebanoff, Christopher A., Ji, Yun, Sukumar, Madhusudhanan, Eil, Robert L., Yu, Zhiya, Spolski, Rosanne, Palmer, Douglas C., Pan, Jenny H., Patel, Shashank J., Macallan, Derek C, Fabozzi, Giulia, Shih, Han-Yu, Kanno, Yuka, Muto, Akihiko, Zhu, Jun, Gattinoni, Luca, O’Shea, John J., Okkenhaug, Klaus, Igarashi, Kazuhiko, Leonard, Warren J., Restifo, Nicholas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918801/
https://www.ncbi.nlm.nih.gov/pubmed/27158840
http://dx.doi.org/10.1038/ni.3441

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