Early Rise of Blood T Follicular Helper Cell Subsets and Baseline Immunity as Predictors of Persisting Late Functional Antibody Responses to Vaccination in Humans

CD4(+) T follicular helper cells (T(FH)) have been identified as the T-cell subset specialized in providing help to B cells for optimal activation and production of high affinity antibody. We recently demonstrated that the expansion of peripheral blood influenza-specific CD4(+)IL-21(+)ICOS1(+) T hel...

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Detalles Bibliográficos
Autores principales: Spensieri, Fabiana, Siena, Emilio, Borgogni, Erica, Zedda, Luisanna, Cantisani, Rocco, Chiappini, Nico, Schiavetti, Francesca, Rosa, Domenico, Castellino, Flora, Montomoli, Emanuele, Bodinham, Caroline L., Lewis, David J., Medini, Duccio, Bertholet, Sylvie, Del Giudice, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918887/
https://www.ncbi.nlm.nih.gov/pubmed/27336786
http://dx.doi.org/10.1371/journal.pone.0157066

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