Contribution of Staphylococcus aureus Coagulases and Clumping Factor A to Abscess Formation in a Rabbit Model of Skin and Soft Tissue Infection

Staphylococcus aureus produces numerous factors that facilitate survival in the human host. S. aureus coagulase (Coa) and von Willebrand factor-binding protein (vWbp) are known to clot plasma through activation of prothrombin and conversion of fibrinogen to fibrin. In addition, S. aureus clumping fa...

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Detalles Bibliográficos
Autores principales: Malachowa, Natalia, Kobayashi, Scott D., Porter, Adeline R., Braughton, Kevin R., Scott, Dana P., Gardner, Donald J., Missiakas, Dominique M., Schneewind, Olaf, DeLeo, Frank R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918888/
https://www.ncbi.nlm.nih.gov/pubmed/27336691
http://dx.doi.org/10.1371/journal.pone.0158293

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