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MUC16 contributes to the metastasis of pancreatic ductal adenocarcinoma through focal adhesion mediated signaling mechanism

MUC16, a heavily glycosylated type-I transmembrane mucin is overexpressed in several cancers including pancreatic ductal adenocarcinoma (PDAC). Previously, we have shown that MUC16 is significantly overexpressed in human PDAC tissues. However, the functional consequences and its role in PDAC is poor...

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Detalles Bibliográficos
Autores principales: Muniyan, Sakthivel, Haridas, Dhanya, Chugh, Seema, Rachagani, Satyanarayana, Lakshmanan, Imayavaramban, Gupta, Suprit, Seshacharyulu, Parthasarathy, Smith, Lynette M., Ponnusamy, Moorthy P., Batra, Surinder K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918949/
https://www.ncbi.nlm.nih.gov/pubmed/27382435
http://dx.doi.org/10.18632/genesandcancer.104