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Identification of a 3(rd) Na(+) Binding Site of the Glycine Transporter, GlyT2
The Na(+)/Cl(-) dependent glycine transporters GlyT1 and GlyT2 regulate synaptic glycine concentrations. Glycine transport by GlyT2 is coupled to the co-transport of three Na(+) ions, whereas transport by GlyT1 is coupled to the co-transport of only two Na(+) ions. These differences in ion-flux coup...
Autores principales: | Subramanian, Nandhitha, Scopelitti, Amanda J., Carland, Jane E., Ryan, Renae M., O’Mara, Megan L., Vandenberg, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919009/ https://www.ncbi.nlm.nih.gov/pubmed/27337045 http://dx.doi.org/10.1371/journal.pone.0157583 |
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