Efficacy and Mechanism of Action of Low Dose Emetine against Human Cytomegalovirus

Infection with human cytomegalovirus (HCMV) is a threat for pregnant women and immunocompromised hosts. Although limited drugs are available, development of new agents against HCMV is desired. Through screening of the LOPAC library, we identified emetine as HCMV inhibitor. Additional studies confirm...

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Detalles Bibliográficos
Autores principales: Mukhopadhyay, Rupkatha, Roy, Sujayita, Venkatadri, Rajkumar, Su, Yu-Pin, Ye, Wenjuan, Barnaeva, Elena, Mathews Griner, Lesley, Southall, Noel, Hu, Xin, Wang, Amy Q., Xu, Xin, Dulcey, Andrés E., Marugan, Juan J., Ferrer, Marc, Arav-Boger, Ravit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919066/
https://www.ncbi.nlm.nih.gov/pubmed/27336364
http://dx.doi.org/10.1371/journal.ppat.1005717

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