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Nanoparticles Effectively Target Rapamycin Delivery to Sites of Experimental Aortic Aneurysm in Rats

Several drugs targeting the pathogenesis of aortic aneurysm have shown efficacy in model systems but not in clinical trials, potentially owing to the lack of targeted drug delivery. Here, we designed a novel drug delivery system using nanoparticles to target the disrupted aortic aneurysm micro-struc...

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Detalles Bibliográficos
Autores principales:	Shirasu, Takuro, Koyama, Hiroyuki, Miura, Yutaka, Hoshina, Katsuyuki, Kataoka, Kazunori, Watanabe, Toshiaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919101/ https://www.ncbi.nlm.nih.gov/pubmed/27336852 http://dx.doi.org/10.1371/journal.pone.0157813

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