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Crystal Structure of the Epithelial Calcium Channel TRPV6

Precise regulation of calcium homeostasis is essential for many physiological functions. The Ca(2+)-selective TRP channels TRPV5 and TRPV6 play vital roles in calcium homeostasis as Ca(2+) uptake channels in epithelial tissues. Detailed structural bases for their assembly and Ca(2+) permeation remai...

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Detalles Bibliográficos
Autores principales: Saotome, Kei, Singh, Appu K., Yelshanskaya, Maria V., Sobolevsky, Alexander I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919205/
https://www.ncbi.nlm.nih.gov/pubmed/27296226
http://dx.doi.org/10.1038/nature17975