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Genome Sequence of Vaccinia virus Strain Lister-Butantan, a Lister Vaccine Variant Used during a Smallpox Eradication Campaign in Brazil

Here, we report the 187.8-kb genome sequence of Vaccinia virus Lister-Butantan, which was used in Brazil during the WHO smallpox eradication campaign. Its genome showed an average similarity of 98.18% with the original Lister isolate, highlighting the low divergence among related Vaccinia virus vacc...

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Detalles Bibliográficos
Autores principales: Assis, Felipe, Trindade, Giliane, Drumond, Betânia, Frace, Mike, Sammons, Scott, Emerson, Ginny, Li, Yu, Carroll, Darin, Batra, Dhwani, Abrahão, Jonatas, Kroon, Erna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919395/
https://www.ncbi.nlm.nih.gov/pubmed/27340056
http://dx.doi.org/10.1128/genomeA.00536-16
Descripción
Sumario:Here, we report the 187.8-kb genome sequence of Vaccinia virus Lister-Butantan, which was used in Brazil during the WHO smallpox eradication campaign. Its genome showed an average similarity of 98.18% with the original Lister isolate, highlighting the low divergence among related Vaccinia virus vaccine strains, even after several passages in animals and cell culture.