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The Effect of Latency Reversal Agents on Primary CD8 + T Cells: Implications for Shock and Kill Strategies for Human Immunodeficiency Virus Eradication
Shock and kill strategies involving the use of small molecules to induce viral transcription in resting CD4 + T cells (shock) followed by immune mediated clearance of the reactivated cells (kill), have been proposed as a method of eliminating latently infected CD4 + T cells. The combination of the h...
Autores principales: | Walker-Sperling, Victoria E., Pohlmeyer, Christopher W., Tarwater, Patrick M., Blankson, Joel N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919475/ https://www.ncbi.nlm.nih.gov/pubmed/27428432 http://dx.doi.org/10.1016/j.ebiom.2016.04.019 |
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