Decreased Usage of Specific Scrib Exons Defines a More Malignant Phenotype of Breast Cancer With Worsened Survival

SCRIB is a polarity regulator known to be abnormally expressed in cancer at the protein level. Here we report that, in breast cancer, an additional and hidden dimension of deregulations exists: an unexpected SCRIB exon usage pattern appears to mark a more malignant tumor phenotype and significantly...

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Detalles Bibliográficos
Autores principales: Metodieva, Gergana, Adoki, Samson, Lausen, Berthold, Metodiev, Metodi V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919504/
https://www.ncbi.nlm.nih.gov/pubmed/27428426
http://dx.doi.org/10.1016/j.ebiom.2016.05.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919504/
https://www.ncbi.nlm.nih.gov/pubmed/27428426
http://dx.doi.org/10.1016/j.ebiom.2016.05.009

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