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The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance
Receptor-interacting protein kinase 3 (RIPK3) mediates necroptosis, a form of programmed cell death that promotes inflammation in various pathological conditions, suggesting that it might be a privileged pharmacological target. However, its function in glucose homeostasis and obesity has been unknow...
Autores principales: | Gautheron, Jérémie, Vucur, Mihael, Schneider, Anne T., Severi, Ilenia, Roderburg, Christoph, Roy, Sanchari, Bartneck, Matthias, Schrammen, Peter, Diaz, Mauricio Berriel, Ehling, Josef, Gremse, Felix, Heymann, Felix, Koppe, Christiane, Lammers, Twan, Kiessling, Fabian, Van Best, Niels, Pabst, Oliver, Courtois, Gilles, Linkermann, Andreas, Krautwald, Stefan, Neumann, Ulf P., Tacke, Frank, Trautwein, Christian, Green, Douglas R., Longerich, Thomas, Frey, Norbert, Luedde, Mark, Bluher, Matthias, Herzig, Stephan, Heikenwalder, Mathias, Luedde, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919522/ https://www.ncbi.nlm.nih.gov/pubmed/27323669 http://dx.doi.org/10.1038/ncomms11869 |
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