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Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription

Histone H3K4 methylation is connected to gene transcription from yeast to humans, but its mechanistic roles in transcription and chromatin dynamics remain poorly understood. We investigated the functions for Set1 and Jhd2, the sole H3K4 methyltransferase and H3K4 demethylase, respectively, in S. cer...

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Detalles Bibliográficos
Autores principales: Ramakrishnan, Saravanan, Pokhrel, Srijana, Palani, Sowmiya, Pflueger, Christian, Parnell, Timothy J., Cairns, Bradley R., Bhaskara, Srividya, Chandrasekharan, Mahesh B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919544/
https://www.ncbi.nlm.nih.gov/pubmed/27325136
http://dx.doi.org/10.1038/ncomms11949