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F16357, a novel protease‐activated receptor 1 antagonist, improves urodynamic parameters in a rat model of interstitial cystitis

BACKGROUND AND PURPOSE: The aims of the present study were to characterize the role of PAR1 in rat bladder under inflammatory conditions and determine whether a selective PAR1 antagonist, F16357, can prevent the pathophysiological symptoms of cyclophosphamide‐induced interstitial cystitis (IC). EXPE...

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Detalles Bibliográficos
Autores principales: Monjotin, N, Gillespie, J, Farrié, M, Le Grand, B, Junquero, D, Vergnolle, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919585/
https://www.ncbi.nlm.nih.gov/pubmed/27111354
http://dx.doi.org/10.1111/bph.13501