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F16357, a novel protease‐activated receptor 1 antagonist, improves urodynamic parameters in a rat model of interstitial cystitis
BACKGROUND AND PURPOSE: The aims of the present study were to characterize the role of PAR1 in rat bladder under inflammatory conditions and determine whether a selective PAR1 antagonist, F16357, can prevent the pathophysiological symptoms of cyclophosphamide‐induced interstitial cystitis (IC). EXPE...
Autores principales: | Monjotin, N, Gillespie, J, Farrié, M, Le Grand, B, Junquero, D, Vergnolle, N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919585/ https://www.ncbi.nlm.nih.gov/pubmed/27111354 http://dx.doi.org/10.1111/bph.13501 |
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