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The anti-angiogenic effect and novel mechanisms of action of Combretastatin A-4
Combretastatin A-4 (CA4) is the lead compound of a relatively new class of vascular disrupting agents that target existing tumor blood vessels. Recent studies showed the CA4 might inhibit angiogenesis. However, the underlying molecular mechanisms by which CA4 exerts its anti-angiogenic effects are n...
Autores principales: | Su, Min, Huang, Jingjia, Liu, Suyou, Xiao, Yuhang, Qin, Xiyuan, Liu, Jia, Pi, Chaoqiong, Luo, Tiao, Li, Jijia, Chen, Xianghui, Luo, Zhiyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919637/ https://www.ncbi.nlm.nih.gov/pubmed/27338725 http://dx.doi.org/10.1038/srep28139 |
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