Cargando…

Everolimus associated interstitial pneumonitis in a liver transplant patient

Drug-induced interstitial lung disease is associated with significant morbidity and mortality. Everolimus is an inhibitor of mTOR, a mammalian target of rapamycin, used as an immunosuppressant agent in solid organ transplant. Everolimus has been associated with interstitial lung disease in solid org...

Descripción completa

Detalles Bibliográficos
Autores principales: Siddiqui, Atif S., Zimmerman, Janice L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919724/
https://www.ncbi.nlm.nih.gov/pubmed/27366673
http://dx.doi.org/10.1016/j.rmcr.2016.06.004
_version_ 1782439295363055616
author Siddiqui, Atif S.
Zimmerman, Janice L.
author_facet Siddiqui, Atif S.
Zimmerman, Janice L.
author_sort Siddiqui, Atif S.
collection PubMed
description Drug-induced interstitial lung disease is associated with significant morbidity and mortality. Everolimus is an inhibitor of mTOR, a mammalian target of rapamycin, used as an immunosuppressant agent in solid organ transplant. Everolimus has been associated with interstitial lung disease in solid organ transplant patients but has been rarely reported in the liver transplant patient population. We report a case of interstitial pneumonitis in a liver transplant patient associated with everolimus which completely resolved after discontinuation of the medication.
format Online
Article
Text
id pubmed-4919724
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-49197242016-06-30 Everolimus associated interstitial pneumonitis in a liver transplant patient Siddiqui, Atif S. Zimmerman, Janice L. Respir Med Case Rep Case Report Drug-induced interstitial lung disease is associated with significant morbidity and mortality. Everolimus is an inhibitor of mTOR, a mammalian target of rapamycin, used as an immunosuppressant agent in solid organ transplant. Everolimus has been associated with interstitial lung disease in solid organ transplant patients but has been rarely reported in the liver transplant patient population. We report a case of interstitial pneumonitis in a liver transplant patient associated with everolimus which completely resolved after discontinuation of the medication. Elsevier 2016-06-14 /pmc/articles/PMC4919724/ /pubmed/27366673 http://dx.doi.org/10.1016/j.rmcr.2016.06.004 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Siddiqui, Atif S.
Zimmerman, Janice L.
Everolimus associated interstitial pneumonitis in a liver transplant patient
title Everolimus associated interstitial pneumonitis in a liver transplant patient
title_full Everolimus associated interstitial pneumonitis in a liver transplant patient
title_fullStr Everolimus associated interstitial pneumonitis in a liver transplant patient
title_full_unstemmed Everolimus associated interstitial pneumonitis in a liver transplant patient
title_short Everolimus associated interstitial pneumonitis in a liver transplant patient
title_sort everolimus associated interstitial pneumonitis in a liver transplant patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919724/
https://www.ncbi.nlm.nih.gov/pubmed/27366673
http://dx.doi.org/10.1016/j.rmcr.2016.06.004
work_keys_str_mv AT siddiquiatifs everolimusassociatedinterstitialpneumonitisinalivertransplantpatient
AT zimmermanjanicel everolimusassociatedinterstitialpneumonitisinalivertransplantpatient