Cargando…
Everolimus associated interstitial pneumonitis in a liver transplant patient
Drug-induced interstitial lung disease is associated with significant morbidity and mortality. Everolimus is an inhibitor of mTOR, a mammalian target of rapamycin, used as an immunosuppressant agent in solid organ transplant. Everolimus has been associated with interstitial lung disease in solid org...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919724/ https://www.ncbi.nlm.nih.gov/pubmed/27366673 http://dx.doi.org/10.1016/j.rmcr.2016.06.004 |
_version_ | 1782439295363055616 |
---|---|
author | Siddiqui, Atif S. Zimmerman, Janice L. |
author_facet | Siddiqui, Atif S. Zimmerman, Janice L. |
author_sort | Siddiqui, Atif S. |
collection | PubMed |
description | Drug-induced interstitial lung disease is associated with significant morbidity and mortality. Everolimus is an inhibitor of mTOR, a mammalian target of rapamycin, used as an immunosuppressant agent in solid organ transplant. Everolimus has been associated with interstitial lung disease in solid organ transplant patients but has been rarely reported in the liver transplant patient population. We report a case of interstitial pneumonitis in a liver transplant patient associated with everolimus which completely resolved after discontinuation of the medication. |
format | Online Article Text |
id | pubmed-4919724 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-49197242016-06-30 Everolimus associated interstitial pneumonitis in a liver transplant patient Siddiqui, Atif S. Zimmerman, Janice L. Respir Med Case Rep Case Report Drug-induced interstitial lung disease is associated with significant morbidity and mortality. Everolimus is an inhibitor of mTOR, a mammalian target of rapamycin, used as an immunosuppressant agent in solid organ transplant. Everolimus has been associated with interstitial lung disease in solid organ transplant patients but has been rarely reported in the liver transplant patient population. We report a case of interstitial pneumonitis in a liver transplant patient associated with everolimus which completely resolved after discontinuation of the medication. Elsevier 2016-06-14 /pmc/articles/PMC4919724/ /pubmed/27366673 http://dx.doi.org/10.1016/j.rmcr.2016.06.004 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Siddiqui, Atif S. Zimmerman, Janice L. Everolimus associated interstitial pneumonitis in a liver transplant patient |
title | Everolimus associated interstitial pneumonitis in a liver transplant patient |
title_full | Everolimus associated interstitial pneumonitis in a liver transplant patient |
title_fullStr | Everolimus associated interstitial pneumonitis in a liver transplant patient |
title_full_unstemmed | Everolimus associated interstitial pneumonitis in a liver transplant patient |
title_short | Everolimus associated interstitial pneumonitis in a liver transplant patient |
title_sort | everolimus associated interstitial pneumonitis in a liver transplant patient |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919724/ https://www.ncbi.nlm.nih.gov/pubmed/27366673 http://dx.doi.org/10.1016/j.rmcr.2016.06.004 |
work_keys_str_mv | AT siddiquiatifs everolimusassociatedinterstitialpneumonitisinalivertransplantpatient AT zimmermanjanicel everolimusassociatedinterstitialpneumonitisinalivertransplantpatient |