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Tales of significance
In this experiment, the authors were interested in testing the effect of a small molecule inhibitor on the ratio of males and females in the offspring of their model Dipteran species. The authors report that in a wild-type population, ~50 % of offspring are male. They then test the effect of treatin...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919870/ https://www.ncbi.nlm.nih.gov/pubmed/27338560 http://dx.doi.org/10.1186/s12915-016-0275-0 |
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| author | Bell, Graham |
| author_facet | Bell, Graham |
| author_sort | Bell, Graham |
| collection | PubMed |
| description | In this experiment, the authors were interested in testing the effect of a small molecule inhibitor on the ratio of males and females in the offspring of their model Dipteran species. The authors report that in a wild-type population, ~50 % of offspring are male. They then test the effect of treating females with the chemical, which they think might affect the male:female ratio compared with the untreated group. They claim that there is a statistically significant increase in the percentage of males produced and conclude that the drug affects sex ratios. |
| format | Online Article Text |
| id | pubmed-4919870 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2016 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-49198702016-06-25 Tales of significance Bell, Graham BMC Biol Comment In this experiment, the authors were interested in testing the effect of a small molecule inhibitor on the ratio of males and females in the offspring of their model Dipteran species. The authors report that in a wild-type population, ~50 % of offspring are male. They then test the effect of treating females with the chemical, which they think might affect the male:female ratio compared with the untreated group. They claim that there is a statistically significant increase in the percentage of males produced and conclude that the drug affects sex ratios. BioMed Central 2016-06-23 /pmc/articles/PMC4919870/ /pubmed/27338560 http://dx.doi.org/10.1186/s12915-016-0275-0 Text en © Bell. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| spellingShingle | Comment Bell, Graham Tales of significance |
| title | Tales of significance |
| title_full | Tales of significance |
| title_fullStr | Tales of significance |
| title_full_unstemmed | Tales of significance |
| title_short | Tales of significance |
| title_sort | tales of significance |
| topic | Comment |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919870/ https://www.ncbi.nlm.nih.gov/pubmed/27338560 http://dx.doi.org/10.1186/s12915-016-0275-0 |
| work_keys_str_mv | AT bellgraham talesofsignificance |