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Exploiting expression patterns across multiple tissues to map expression quantitative trait loci

BACKGROUND: In order to better understand complex diseases, it is important to understand how genetic variation in the regulatory regions affects gene expression. Genetic variants found in these regulatory regions have been shown to activate transcription in a tissue-specific manner. Therefore, it i...

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Detalles Bibliográficos
Autores principales: Acharya, Chaitanya R., McCarthy, Janice M., Owzar, Kouros, Allen, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919894/
https://www.ncbi.nlm.nih.gov/pubmed/27341818
http://dx.doi.org/10.1186/s12859-016-1123-5

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