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Hypoxia-Responsive Mir-301a and Mir-301b Promote Radioresistance of Prostate Cancer Cells via Downregulating NDRG2

BACKGROUND: MiR-301a and miR-301b are 2 oncomiRs involved in multiple types of cancer. In this study, we explored the expression change of miR-301a and miR-301b in prostate cancer cells in hypoxia and studied their regulation of autophagy and radiosensitivity of prostate cancer cells. MATERIAL/METHO...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Liu, Mingbo, Guan, Yawei, Wu, Qingwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920099/
https://www.ncbi.nlm.nih.gov/pubmed/27327120
http://dx.doi.org/10.12659/MSM.896832