Cas-Database: web-based genome-wide guide RNA library design for gene knockout screens using CRISPR-Cas9

Motivation: CRISPR-derived RNA guided endonucleases (RGENs) have been widely used for both gene knockout and knock-in at the level of single or multiple genes. RGENs are now available for forward genetic screens at genome scale, but single guide RNA (sgRNA) selection at this scale is difficult. Resu...

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Detalles Bibliográficos
Autores principales: Park, Jeongbin, Kim, Jin-Soo, Bae, Sangsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920116/
https://www.ncbi.nlm.nih.gov/pubmed/27153724
http://dx.doi.org/10.1093/bioinformatics/btw103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920116/
https://www.ncbi.nlm.nih.gov/pubmed/27153724
http://dx.doi.org/10.1093/bioinformatics/btw103

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