Identification of benzopyrone as a common structural feature in compounds with anti-inflammatory activity in a zebrafish phenotypic screen

Neutrophils are essential for host defence and are recruited to sites of inflammation in response to tissue injury or infection. For inflammation to resolve, these cells must be cleared efficiently and in a controlled manner, either by apoptosis or reverse migration. If the inflammatory response is...

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Detalles Bibliográficos
Autores principales: Robertson, Anne L., Ogryzko, Nikolay V., Henry, Katherine M., Loynes, Catherine A., Foulkes, Matthew J., Meloni, Marco M., Wang, Xingang, Ford, Christopher, Jackson, Malcolm, Ingham, Philip W., Wilson, Heather L., Farrow, Stuart N., Solari, Roberto, Flower, Roderick J., Jones, Simon, Whyte, Moira K. B., Renshaw, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920152/
https://www.ncbi.nlm.nih.gov/pubmed/27079522
http://dx.doi.org/10.1242/dmm.024935

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