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Tissue- and stage-specific Wnt target gene expression is controlled subsequent to β-catenin recruitment to cis-regulatory modules

Key signalling pathways, such as canonical Wnt/β-catenin signalling, operate repeatedly to regulate tissue- and stage-specific transcriptional responses during development. Although recruitment of nuclear β-catenin to target genomic loci serves as the hallmark of canonical Wnt signalling, mechanisms...

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Detalles Bibliográficos
Autores principales: Nakamura, Yukio, de Paiva Alves, Eduardo, Veenstra, Gert Jan C., Hoppler, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920159/
https://www.ncbi.nlm.nih.gov/pubmed/27068107
http://dx.doi.org/10.1242/dev.131664