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Impaired Sarcoplasmic Reticulum Calcium Uptake and Release Promote Electromechanically and Spatially Discordant Alternans: A Computational Study
Cardiac electrical dynamics are governed by cellular-level properties, such as action potential duration (APD) restitution and intracellular calcium (Ca) handling, and tissue-level properties, including conduction velocity restitution and cell–cell coupling. Irregular dynamics at the cellular level...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Libertas Academica
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920205/ https://www.ncbi.nlm.nih.gov/pubmed/27385917 http://dx.doi.org/10.4137/CMC.S39709 |