Mapping the Hsp90 Genetic Network Reveals Ergosterol Biosynthesis and Phosphatidylinositol-4-Kinase Signaling as Core Circuitry Governing Cellular Stress

Candida albicans is a leading human fungal pathogen that causes life-threatening systemic infections. A key regulator of C. albicans stress response, drug resistance, morphogenesis, and virulence is the molecular chaperone Hsp90. Targeting Hsp90 provides a powerful strategy to treat fungal infection...

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Detalles Bibliográficos
Autores principales: O’Meara, Teresa R., Veri, Amanda O., Polvi, Elizabeth J., Li, Xinliu, Valaei, Seyedeh Fereshteh, Diezmann, Stephanie, Cowen, Leah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920384/
https://www.ncbi.nlm.nih.gov/pubmed/27341673
http://dx.doi.org/10.1371/journal.pgen.1006142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920384/
https://www.ncbi.nlm.nih.gov/pubmed/27341673
http://dx.doi.org/10.1371/journal.pgen.1006142

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