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Hyperglycemia Impairs Neutrophil-Mediated Bacterial Clearance in Mice Infected with the Lyme Disease Pathogen
Insulin-insufficient type 1 diabetes is associated with attenuated bactericidal function of neutrophils, which are key mediators of innate immune responses to microbes as well as pathological inflammatory processes. Neutrophils are central to immune responses to the Lyme pathogen Borrelia burgdorfer...
Autores principales: | Javid, Ashkan, Zlotnikov, Nataliya, Pětrošová, Helena, Tang, Tian Tian, Zhang, Yang, Bansal, Anil K., Ebady, Rhodaba, Parikh, Maitry, Ahmed, Mijhgan, Sun, Chunxiang, Newbigging, Susan, Kim, Yae Ram, Santana Sosa, Marianna, Glogauer, Michael, Moriarty, Tara J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920391/ https://www.ncbi.nlm.nih.gov/pubmed/27340827 http://dx.doi.org/10.1371/journal.pone.0158019 |
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