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Targeted HIV-1 Latency Reversal Using CRISPR/Cas9-Derived Transcriptional Activator Systems

CRISPR/Cas9 technology is currently considered the most advanced tool for targeted genome engineering. Its sequence-dependent specificity has been explored for locus-directed transcriptional modulation. Such modulation, in particular transcriptional activation, has been proposed as key approach to o...

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Detalles Bibliográficos
Autores principales:	Bialek, Julia K., Dunay, Gábor A., Voges, Maike, Schäfer, Carola, Spohn, Michael, Stucka, Rolf, Hauber, Joachim, Lange, Ulrike C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920395/ https://www.ncbi.nlm.nih.gov/pubmed/27341108 http://dx.doi.org/10.1371/journal.pone.0158294

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