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An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection

Salmonella Typhimurium (S.Tm) is a common cause of self-limiting diarrhea. The mucosal inflammation is thought to arise from a standoff between the pathogen's virulence factors and the host's mucosal innate immune defenses, particularly the mucosal NAIP/NLRC4 inflammasome. However, it had...

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Detalles Bibliográficos
Autores principales: Müller, Anna A., Dolowschiak, Tamas, Sellin, Mikael E., Felmy, Boas, Verbree, Carolin, Gadient, Sandra, Westermann, Alexander J., Vogel, Jörg, LeibundGut-Landmann, Salome, Hardt, Wolf-Dietrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920399/
https://www.ncbi.nlm.nih.gov/pubmed/27341123
http://dx.doi.org/10.1371/journal.ppat.1005723