Donor-Recipient Matching for KIR Genotypes Reduces Chronic GVHD and Missing Inhibitory KIR Ligands Protect against Relapse after Myeloablative, HLA Matched Hematopoietic Cell Transplantation

BACKGROUND: Allogeneic hematopoietic cell transplantation (HCT) can be curative for many hematologic diseases. However, complications such as graft-versus-host disease (GVHD) and relapse of primary malignancy remain significant and are the leading causes of morbidity and mortality. Effects of killer...

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Detalles Bibliográficos
Autores principales: Faridi, Rehan Mujeeb, Kemp, Taylor J., Dharmani-Khan, Poonam, Lewis, Victor, Tripathi, Gaurav, Rajalingam, Raja, Daly, Andrew, Berka, Noureddine, Storek, Jan, Masood Khan, Faisal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920429/
https://www.ncbi.nlm.nih.gov/pubmed/27341514
http://dx.doi.org/10.1371/journal.pone.0158242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920429/
https://www.ncbi.nlm.nih.gov/pubmed/27341514
http://dx.doi.org/10.1371/journal.pone.0158242

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