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Donor-Recipient Matching for KIR Genotypes Reduces Chronic GVHD and Missing Inhibitory KIR Ligands Protect against Relapse after Myeloablative, HLA Matched Hematopoietic Cell Transplantation
BACKGROUND: Allogeneic hematopoietic cell transplantation (HCT) can be curative for many hematologic diseases. However, complications such as graft-versus-host disease (GVHD) and relapse of primary malignancy remain significant and are the leading causes of morbidity and mortality. Effects of killer...
Autores principales: | Faridi, Rehan Mujeeb, Kemp, Taylor J., Dharmani-Khan, Poonam, Lewis, Victor, Tripathi, Gaurav, Rajalingam, Raja, Daly, Andrew, Berka, Noureddine, Storek, Jan, Masood Khan, Faisal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920429/ https://www.ncbi.nlm.nih.gov/pubmed/27341514 http://dx.doi.org/10.1371/journal.pone.0158242 |
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