SET9-Mediated Regulation of TGF-β Signaling Links Protein Methylation to Pulmonary Fibrosis

TGF-β signaling regulates a variety of cellular processes, including proliferation, apoptosis, differentiation, immune responses, and fibrogenesis. Here, we describe a lysine methylation-mediated mechanism that controls the pro-fibrogenic activity of TGF-β. We find that the methyltransferase Set9 po...

Descripción completa

Detalles Bibliográficos
Autores principales: Elkouris, Maximilianos, Kontaki, Haroula, Stavropoulos, Athanasios, Antonoglou, Anastasia, Nikolaou, Kostas C., Samiotaki, Martina, Szantai, Eszter, Saviolaki, Dimitra, Brown, Peter J., Sideras, Paschalis, Panayotou, George, Talianidis, Iannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920893/
https://www.ncbi.nlm.nih.gov/pubmed/27292644
http://dx.doi.org/10.1016/j.celrep.2016.05.051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920893/
https://www.ncbi.nlm.nih.gov/pubmed/27292644
http://dx.doi.org/10.1016/j.celrep.2016.05.051

Ejemplares similares