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Bidirectional Crosstalk between C5a Receptors and the NLRP3 Inflammasome in Macrophages and Monocytes

C5a is an inflammatory mediator generated by complement activation that positively regulates various arms of immune defense, including Toll-like receptor 4 (TLR4) signaling. The NOD-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome is activated by pathogen products and cellular/ti...

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Detalles Bibliográficos
Autores principales:	Haggadone, Mikel D., Grailer, Jamison J., Fattahi, Fatemeh, Zetoune, Firas S., Ward, Peter A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921141/ https://www.ncbi.nlm.nih.gov/pubmed/27382187 http://dx.doi.org/10.1155/2016/1340156

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