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CD138 and CD31 Double-Positive Cells Comprise the Functional Antibody-Secreting Plasma Cell Compartment in Primate Bone Marrow
Plasma cells (PCs) are defined as terminally differentiated B cells that secrete large amounts of immunoglobulin (Ig). PCs that reside in the bone marrow (BM) are responsible for maintaining long-term antibody (Ab) responses after infection and vaccination, while PCs present in the blood are general...
Autores principales: | Martinez-Murillo, Paola, Pramanik, Lotta, Sundling, Christopher, Hultenby, Kjell, Wretenberg, Per, Spångberg, Mats, Karlsson Hedestam, Gunilla B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921460/ https://www.ncbi.nlm.nih.gov/pubmed/27446073 http://dx.doi.org/10.3389/fimmu.2016.00242 |
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