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Hypoxia-Inducible Factor (HIF) as a Target for Novel Therapies in Rheumatoid Arthritis
Hypoxia is an important micro-environmental characteristic of rheumatoid arthritis (RA). Hypoxia-inducible factors (HIF) are key transcriptional factors that are highly expressed in RA synovium to regulate the adaptive responses to this hypoxic milieu. Accumulating evidence supports hypoxia and HIFs...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921475/ https://www.ncbi.nlm.nih.gov/pubmed/27445820 http://dx.doi.org/10.3389/fphar.2016.00184 |