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Transient Fcho1/2⋅Eps15/R⋅AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding
Clathrin-coated vesicles form by rapid assembly of discrete coat constituents into a cargo-sorting lattice. How the sequential phases of coat construction are choreographed is unclear, but transient protein-protein interactions mediated by short interaction motifs are pivotal. We show that arrayed A...
Autores principales: | Ma, Li, Umasankar, Perunthottathu K., Wrobel, Antoni G., Lymar, Anastasia, McCoy, Airlie J., Holkar, Sachin S., Jha, Anupma, Pradhan-Sundd, Tirthadipa, Watkins, Simon C., Owen, David J., Traub, Linton M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921775/ https://www.ncbi.nlm.nih.gov/pubmed/27237791 http://dx.doi.org/10.1016/j.devcel.2016.05.003 |
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