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Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets

OBJECTIVE: Complex local crosstalk amongst endocrine cells within the islet ensures tight coordination of their endocrine output. This is illustrated by the recent demonstration that the negative feedback control by delta cells within pancreatic islets determines the homeostatic set-point for plasma...

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Detalles Bibliográficos
Autores principales: DiGruccio, Michael R., Mawla, Alex M., Donaldson, Cynthia J., Noguchi, Glyn M., Vaughan, Joan, Cowing-Zitron, Christopher, van der Meulen, Talitha, Huising, Mark O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921781/
https://www.ncbi.nlm.nih.gov/pubmed/27408771
http://dx.doi.org/10.1016/j.molmet.2016.04.007