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Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets
OBJECTIVE: Complex local crosstalk amongst endocrine cells within the islet ensures tight coordination of their endocrine output. This is illustrated by the recent demonstration that the negative feedback control by delta cells within pancreatic islets determines the homeostatic set-point for plasma...
Autores principales: | DiGruccio, Michael R., Mawla, Alex M., Donaldson, Cynthia J., Noguchi, Glyn M., Vaughan, Joan, Cowing-Zitron, Christopher, van der Meulen, Talitha, Huising, Mark O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921781/ https://www.ncbi.nlm.nih.gov/pubmed/27408771 http://dx.doi.org/10.1016/j.molmet.2016.04.007 |
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