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Autonomous interconversion between adult pancreatic α-cells and β-cells after differential metabolic challenges

BACKGROUND: Evidence hints at the ability of β-cells to emerge from non-β-cells upon genetic or pharmacological interventions. However, their quantitative contributions to the process of autonomous β-cell regeneration without genetic or pharmacological manipulations remain to be determined. METHODS...

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Detalles Bibliográficos
Autores principales: Ye, Risheng, Wang, Miao, Wang, Qiong A., Spurgin, Stephen B., Wang, Zhao V., Sun, Kai, Scherer, Philipp E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921793/
https://www.ncbi.nlm.nih.gov/pubmed/27408770
http://dx.doi.org/10.1016/j.molmet.2016.05.001