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Focused ultrasound-enhanced intranasal brain delivery of brain-derived neurotrophic factor
The objective of this study was to unveil the potential mechanism of focused ultrasound (FUS)-enhanced intranasal (IN) brain drug delivery and assess its feasibility in the delivery of therapeutic molecules. Delivery outcomes of fluorescently-labeled dextrans to mouse brains by IN administration eit...
Autores principales: | Chen, Hong, Yang, Georgiana Zong Xin, Getachew, Hoheteberhan, Acosta, Camilo, Sierra Sánchez, Carlos, Konofagou, Elisa E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921840/ https://www.ncbi.nlm.nih.gov/pubmed/27345430 http://dx.doi.org/10.1038/srep28599 |
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