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Thioredoxin reductase 1 suppresses adipocyte differentiation and insulin responsiveness

Recently thioredoxin reductase 1 (TrxR1), encoded by Txnrd1, was suggested to modulate glucose and lipid metabolism in mice. Here we discovered that TrxR1 suppresses insulin responsiveness, anabolic metabolism and adipocyte differentiation. Immortalized mouse embryonic fibroblasts (MEFs) lacking Txn...

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Detalles Bibliográficos
Autores principales:	Peng, Xiaoxiao, Giménez-Cassina, Alfredo, Petrus, Paul, Conrad, Marcus, Rydén, Mikael, Arnér, Elias S. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921861/ https://www.ncbi.nlm.nih.gov/pubmed/27346647 http://dx.doi.org/10.1038/srep28080

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