The insect repellent N,N-diethyl-m-toluamide (DEET) induces angiogenesis via allosteric modulation of the M3 muscarinic receptor in endothelial cells

The insect repellent N,N-diethyl-m-toluamide (DEET) has been reported to inhibit AChE (acetylcholinesterase) and to possess potential carcinogenic properties with excessive vascularization. In the present paper, we demonstrate that DEET specifically stimulates endothelial cells that promote angiogen...

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Detalles Bibliográficos
Autores principales: Legeay, Samuel, Clere, Nicolas, Hilairet, Grégory, Do, Quoc-Tuan, Bernard, Philippe, Quignard, Jean-François, Apaire-Marchais, Véronique, Lapied, Bruno, Faure, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921870/
https://www.ncbi.nlm.nih.gov/pubmed/27345502
http://dx.doi.org/10.1038/srep28546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921870/
https://www.ncbi.nlm.nih.gov/pubmed/27345502
http://dx.doi.org/10.1038/srep28546

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