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Induction of a stable sigma factor SigR by translation-inhibiting antibiotics confers resistance to antibiotics
Antibiotic-producing streptomycetes are rich sources of resistance mechanisms against endogenous and exogenous antibiotics. An ECF sigma factor σ(R) (SigR) is known to govern the thiol-oxidative stress response in Streptomyces coelicolor. Amplification of this response is achieved by producing an un...
Autores principales: | Yoo, Ji-Sun, Oh, Gyeong-Seok, Ryoo, Sungweon, Roe, Jung-Hye |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921905/ https://www.ncbi.nlm.nih.gov/pubmed/27346454 http://dx.doi.org/10.1038/srep28628 |
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