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Leptin promotes VEGF-C production and induces lymphangiogenesis by suppressing miR-27b in human chondrosarcoma cells

Chondrosarcoma is the second most frequently occurring type of bone malignancy that is characterized by the distant metastasis propensity. Vascular endothelial growth factor-C (VEGF-C) is the chief lymphangiogenic mediator, and makes crucial contributions to tumor lymphangiogenesis. Leptin is an adi...

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Detalles Bibliográficos
Autores principales:	Yang, Wei-Hung, Chang, An-Chen, Wang, Shih-Wei, Wang, Shoou-Jyi, Chang, Yung-Sen, Chang, Tzu-Ming, Hsu, Shao-Keh, Fong, Yi-Chin, Tang, Chih-Hsin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921910/ https://www.ncbi.nlm.nih.gov/pubmed/27345723 http://dx.doi.org/10.1038/srep28647

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