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A theoretical estimate for nucleotide sugar demand towards Chinese Hamster Ovary cellular glycosylation

Glycosylation greatly influences the safety and efficacy of many of the highest-selling recombinant therapeutic proteins (rTPs). In order to define optimal cell culture feeding strategies that control rTP glycosylation, it is necessary to know how nucleotide sugars (NSs) are consumed towards host ce...

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Detalles Bibliográficos
Autores principales:	del Val, Ioscani Jimenez, Polizzi, Karen M., Kontoravdi, Cleo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921913/ https://www.ncbi.nlm.nih.gov/pubmed/27345611 http://dx.doi.org/10.1038/srep28547

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