Efficacy of Intraperitoneal Administration of PEGylated NELL-1 for Bone Formation

Systemically delivered NEL-like molecule-1 (NELL-1), a potent pro-osteogenic protein, promotes bone formation in healthy and osteoporotic mouse models. PEGylation of NELL-1 (NELL-PEG) increases the half-life of the protein in a mouse model without compromising its osteogenic potential, thereby impro...

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Detalles Bibliográficos
Autores principales: Tanjaya, Justine, Zhang, Yulong, Lee, Soonchul, Shi, Jiayu, Chen, Eric, Ang, Pia, Zhang, Xinli, Tetradis, Sotirios, Ting, Kang, Wu, Benjamin, Soo, Chia, Kwak, Jin Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921932/
https://www.ncbi.nlm.nih.gov/pubmed/27354930
http://dx.doi.org/10.1089/biores.2016.0018

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