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Lack of AKT in adipocytes causes severe lipodystrophy
OBJECTIVE: Adipose depot mass is tightly regulated to maintain energy homeostasis. AKT is a critical kinase in the insulin-signaling cascade that is required for the process of adipogenesis in vitro. However, the role of AKT in the maintenance and/or function of mature adipocytes in vivo had not bee...
Autores principales: | Shearin, Abigail L., Monks, Bobby R., Seale, Patrick, Birnbaum, Morris J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921941/ https://www.ncbi.nlm.nih.gov/pubmed/27408773 http://dx.doi.org/10.1016/j.molmet.2016.05.006 |
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